禅世界论坛

<- 社交登陆。【论坛使用帮助】
耸人听闻的所谓新闻“別再吃!美熱銷胃藥...
 
Notifications
Clear all

耸人听闻的所谓新闻“別再吃!美熱銷胃藥确认致癌超标3000倍!”

1
1 Users
0 Likes
816 查看
Many
 Many
(@many)
Illustrious Member Admin Registered
已加入: 5年 前
帖子: 9755
Topic starter  

某媒体发布耸人听闻的所谓新闻“別再吃!美熱銷胃藥确认致癌超标3000倍!”,将在Zantac某些批次中发现的NDMA,与Zantac和其他大众化的含ranitidine的非处方药混为一谈。

当前FDA的声明不呼吁人们停止使用ranitidine药品;在服用ranitidine处方药的而希望停止服用的病人们应该和他们的健康关怀专业人员谈论其他治疗选项。

 


【转载】

Statement alerting patients and health care professionals of NDMA found in samples of ranitidine

https://www.fda.gov/news-events/press-announcements/statement-alerting-patients-and-health-care-professionals-ndma-found-samples-ranitidine

For Immediate Release:

September 13, 2019
Statement From:
Director - Center for Drug Evaluation and Research
 

Janet Woodcock M.D.

Español

The U.S. Food and Drug Administration has learned that some ranitidine medicines, including some products commonly known as the brand-name drug Zantac, contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA) at low levels. NDMA is classified as a probable human carcinogen (a substance that could cause cancer) based on results from laboratory tests. NDMA is a known environmental contaminant and found in water and foods, including meats, dairy products, and vegetables.

The FDA has been investigating NDMA and other nitrosamine impurities in blood pressure and heart failure medicines called Angiotensin II Receptor Blockers (ARBs) since last year. In the case of ARBs, the FDA has recommended numerous recalls as it discovered unacceptable levels of nitrosamines.

When the agency identifies a problem, it takes appropriate action quickly to protect patients. The FDA is evaluating whether the low levels of NDMA in ranitidine pose a risk to patients. FDA will post that information when it is available.

Patients should be able to trust that their medicines are as safe as they can be and that the benefits of taking them outweigh any risk to their health. Although NDMA may cause harm in large amounts, the levels the FDA is finding in ranitidine from preliminary tests barely exceed amounts you might expect to find in common foods.

Ranitidine is an over-the-counter (OTC) and prescription drug. Ranitidine is an H2 (histamine-2) blocker, which decreases the amount of acid created by the stomach. Over-the-counter ranitidine is approved to prevent and relieve heartburn associated with acid ingestion and sour stomach. Prescription ranitidine is approved for multiple indications, including treatment and prevention of ulcers of the stomach and intestines and treatment of gastroesophageal reflux disease.

The agency is working with international regulators and industry partners to determine the source of this impurity in ranitidine. The agency is examining levels of NDMA in ranitidine and evaluating any possible risk to patients. The FDA will take appropriate measures based on the results of the ongoing investigation. The agency will provide more information as it becomes available.

The FDA is not calling for individuals to stop taking ranitidine at this time; however, patients taking prescription ranitidine who wish to discontinue use should talk to their health care professional about other treatment options. People taking OTC ranitidine could consider using other OTC medicines approved for their condition. There are multiple drugs on the market that are approved for the same or similar uses as ranitidine.

Consumers and health care professionals should report any adverse reactions with ranitidine to the FDA’s MedWatch program to help the agency better understand the scope of the problem:

  • Complete and submit the report online at www.fda.gov/medwatch/report.htm
  • Download and complete the appropriate form, then submit it via fax at 1-800-FDA-0178

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

 

別再吃!美熱銷胃藥确认致癌超标3000倍!

文章来源: 北美e生活 于 2019-10-06 18:48:11 - 新闻取自各大新闻媒体,新闻内容并不代表本网立场!
(被阅读 3079
 




这是一款风靡全球的胃药,它有一个引以为傲的统计数字2018年一年内,医生开出2500万份该药品处方单。

而现在,它又有了一个让人不寒而栗的数字致癌物,超标3000倍。在澳洲,在中国,在美国均有大量销售。









这款胃药,华人在吃,还当成放心药在吃,澳洲人在吃,欧洲人在吃,美国人也在吃,现在,即将变成死人在吃了。记住这个名字,Zantac,中文善胃得。







Dailymail:FDA宣布,Zantac含有不可接受的致癌物,每年有成千上万盒药物被售出。




2019年9月13日,美国FDA药监局和欧洲药品安全局乱成了一锅粥。




药物中怎么会有这种物质?它不该出现在胃药里的!

它,从何而来?在查看2018年,医院对该药物的处方统计后,FDA的工作人员一个个地瘫坐下来,这天发生的事情,堪比世界末日。









2500万份处方,还只是处方,不包括患者自行购买数量,这意味着,2500万人很可能即将患癌。







CNBC







SMH









纽约时报

这一次,FDA和欧洲药品安全局检查出的物质,名叫NDMA。

NDMA有经胎盘致癌作用,多种短期致突变试验出现阳性结果。

美国政府工业卫生学家协会(ACGIH)将NDMA列为人类可疑化学致癌物。







它是从哪被检测出来的呢?

从一款风靡全球的胃药中,它叫Zantac,中文善胃得。







沃尔玛超市的货架上,摆放着Zantac胃药,仅剩一盒





风靡全球的胃药





Zantac产自墨西哥,药品中的活性成分来自西班牙。

在世界范围内,Zantac的影响力可谓是胃药中的板蓝根了,只要有胃病,许多小伙伴第一个想到的,就是Zantac。而现在,这款胃病患者的必备之药却成了剧毒之药,治好了胃病,却迎来了胃癌









Zantac的贩售范围有多广呢?它的广泛你想都想不到。Zantac的不同产品有着药品成分含量的区别,故,Zantac及其仿制药分为处方药与非处方药。Zantac的处方药,只有在医生的指导下才能购买和服用,哪怕是这样,一年内,各地的医院也开出了2500万份Zantac处方。







而流传更广于市场的,是Zantac的非处方药,购买Zantac非处方药,就像买板蓝根那样简单。只要有药房、有超市,其货架上就摆放着Zantac胃药。在澳洲,各大超市的药品货架上都有Zantac的踪迹,







CVS上所售Zantac

比如Costco超市中,就有两款Zantac胃药在售。









Costco中的Zantac







Woolworths货架上的Zantac

上图是澳大利亚Woolworths超市货架上的Zantac胃药,它们在超市货架上整齐地摆放着,一旁摆放着的是Acid创可贴,这种药,和创可贴一样唾手可得。







Chemistwarehouse正在售卖Zantac

在澳洲的Chemistwarehouse中,也摆放着Zantac胃药,一同摆放在周围的产品也是生活中的常用保健品,Zantac,太容易进入我们的生活了。









不只是在澳洲,Zantac这款胃药也通过各地的代购,随时随刻进入了华人们的生活圈。

只要在Google搜索栏里搜索,Zantac代购,你可以获得约3190条搜索结果,内容,全都是Zantac胃药的广告和代购信息。







由于Zantac的药效明显,且所谓的口碑不错,现代社会中,人们的生活饮食习惯又容易紊乱,导致胃状态不佳,这款便宜又常见的胃药自然而然成了华人们回国送礼的首选。在中国,它的名字叫善胃得,







在某网购平台上,它实在太稀疏平常了。









然而,谁都没想到的是,你好心好意拱手相送的礼物,竟然是致癌毒药!











3000倍致癌物





据美国药品食品管理局(FDA)表示,部分Zantac胃药被发现含有微量的不纯物N-亚硝基二甲胺(NDMA)成分,由于此成分可能有致癌疑虑,使得相关药品都被下架。







欧洲药物管理局则表示,正在评估这些数据,将尽快推算出患者使用多少药品才会致癌的具体信息。目前,美国将停售畅销的胃灼热治疗药物「善胃得」(Zantac)、和主要成份为雷尼替丁(ranitidine)的自有品牌药品,据路透社报导,美国药妆连锁企业CVS Health Corp表示,由于此成分(NDMA)可能有致癌疑虑,使得相关药品都被下架。









NDMA对于一些患者来说并不陌生,前段时间的降压药致癌风波,罪魁祸首就是这个NDMA。我们上面提到过,NDMA被人类可疑化学致癌物,可引起肝脏损伤、血液血小板计数下降、转氨酶浓度升高,还包括头痛,发烧,呕吐,腹痛,分散性皮下出血,嗜睡,恶心,腹泻等症状。较小剂量的长期暴露也可能增加肝癌风险。







而只要剂量足,万物皆有毒,3000倍超标,剂量够不够足?







在2018年,部分降压药因含17微克NDMA而被全面大量召回,因为美国FDA对NDMA的用量规定为,1微克以下。而如今,Zantac及其仿制药物中所含有的NDMA竟然高达了3000微克,不如不要吃药了,直接吃NDMA吧,都怪Zantac这款药,把NDMA都搞得不纯了。









那么,NDMA是怎么被混入Zantac的呢?FDA表示,我也不知道

据FDA调查表示,致癌物NDMA是如何进入这些药物中的原因一直是个谜。而目前有人猜测,由于Zantac是医药公司Sanofi的产品品牌,除胃药外还有感冒药之类的药品。







有问题的Zantac胃药主要可能含有致癌的NDMA成份,这个应该不是胃药的组成部分,可能在药物制造过程中受污染或其他原因造成的。其他品牌如kirkland的同种仿制药,只要不是来自同一产地或生产厂家就可以认为是安全的。







食品,被查出含有致癌物,洗衣粉,也被查出含有致癌物,连治病的药品,也纷纷被查出致癌物,小伙伴们用药用膳,一定得注意了啊,一不小心,就病从口入了。









美国FDA和欧洲药品安全局联合发布声明,Zantac和其他含有雷尼替丁的产品因含有过量NDMA而暂停贩售。其中,Zantac胃药中的NDMA据称超标3000倍,然而NDMA成分一般不存在于胃药中,故,此次事件被怀疑是药品污染导致。







目前,FDA强烈建议大家使用其他药物代替Zantac,不要再继续服用与Zantac有关的胃药。








引用
Share:

【声明】:禅世界论坛尊重言论自由,任何人可讨论佛学、政经、生活和科技等话题。在言论发表前请根据常识和法规自审。论坛管理员和版主有权删除任何不当内容。使用本论坛即表示接受【禅世界论坛规则】【论坛使用帮助】。 【禅世界免责声明】


【Chanworld.org】2017.06.06-2021.04.30-MG